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Derived No Effect Level (DNEL)
A DNEL is the level of exposure to the substance below which no adverse effects are expected to occur. It is therefore the level of exposure to the substance above which humans should not be exposed. DNEL is a derived level of exposure because it is normally calculated on the basis of available dose descriptors from animal studies such as No Observed adverse effect Levels (NOAELs) or benchmark doses (BMDs). (Source: REACH Glossary)
DNEL

Derived No effect Level. For non-threshold effects, the underlying assumption is that a no-effect-level cannot be established and a DNEL therefore expresses an exposure level corresponding to a low, possibly theoretical risk, which should be seen as a tolerable risk. (Source: REACH Glossary)