Lexikon
an experimental exposure of a previously treated subject to a test substance following an induction period, to determine if the subject reacts in a hypersensitive manner.
exposure is the concentration or dose of the substance to which humans and the environment are or may be exposed by producing or using the chemical substance or by using contaminated land.
exposure assessment aims to make a quantitative or qualitative estimate of the dose / concentration, which the users are exposed to. exposure assessment under REACH consists of two steps: 1) Development of exposure Scenarios and 2) exposure Estimation, which have to be iterated until it can be concluded that the resulting exposure scenarios would ensure adequate control of risks upon implementation. (Source: REACH Glossary)
The Exposure Information required for substances registered in the 1 to 10 tonne band is defined in Annex VI, 6, of REACH, and is given in the table below.
This information is required in place of the CSR which is required for substances in higher tonnage bands.
| Annex VI clause | Exposure Information required |
| 6.1 | Main use category |
6.1.1 | (a) Industrial use; (b) Professional; (c) Consumer use |
6.1.2 | Specification for industrial and professional use: |
| 6.2 | Significant routes of exposure |
6.2.1 | Human exposure: (a) oral; (b) dermal; (c) inhalatory. |
6.2.2 | Environmental exposure: (a) water; (b) air; (c) solid waste; (d) soil. |
| 6.3 | Pattern of exposure: (a) accidental; (b) occasional; (c) continuous/frequent |
Source: http://www.reach-serv.com/index.php?option=com_content&task=view&id=160&Itemid=64
set of conditions, including operational conditions and risk management measures, that describe how the substance is manufactured or used during its life-cycle and how the manufacturer or importer controls, or recommends downstream users to control exposure of humans and the environment. These exposure scenarios may cover one specific process or use or several processes or uses as appropriate. Source: REACH Glossary
a study that uses biomedical testing or the measurement of a substance, its metabolite, or another marker of exposure in human body fluids or tissues to confirm human exposure to a hazardous substance.
a method used in skin sensitization tests. The test animals are initially exposed to the test substance by intradermal injection and/or epidermal application (induction exposure). Following a rest period of 10 to 14 days, during which an immune response may develop.