Lexikon

substances of very high concern, which are very persistent (very difficult to break down) and very bio-accumulative in living organisms. Annex XIII defines criteria for the identification of vPvBs and Annex I lays down general provisions for their assessment. vPvBs may be included in Annex XIV and by that be made subject to authorisation. (Source: REACH Glossary)

see very Persistent and very Bioccumulative Substances