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transgenic desease models

transgenic animals may be produced as disease models, meaning genetically manipulated animals, which exhibit disease symptoms so that effective treatment can be studied. For example, Harvard scientists made a major scientific breakthrough when they received a U.S. patent (the company DuPont holds exclusive rights to its use) for a genetically engineered mouse, called OncoMouse® or the Harvard mouse, carrying a gene that promotes the development of various human cancers.